Down’s Syndrome Related to Maternal Old Age!
Are you aware of the fact that late maternal age can lead to a number of chromosomal abnormalities in the developing embryo?
Increasing maternal and paternal age can predispose the offspring( developing baby) to a number of chromosomal diseases such as Down’s syndrome, Marfan syndrome and Achondroplasia.
Advanced Maternal Age: ( Above 35 years):
The most common chromosomal abnormality associated with increasing maternal age is Down’s syndrome. The actual cause of Down’s syndrome is Non-dysjunction of the chromosomes during meiosis , the incidence of which is increased with the advancement in mothers age. Children with Down’s syndrome have specific features:
Clinical Findings in Down’s Syndrome patients:
1- Mental retardation (severe)
2- Epicanthal folds
3- Brushfield Spots
4- Simian crease
5- Decreased alpha fetoprotein in blood is also associated with Down’s patients.
Hope this article was informative. Find the abnormalites related to old paternal age as in my next article.
Liked it
momofplenty | Jul 19, 2012 | Reply
Nature seems to be aware of this, as most women are more fertile in younger years, and Doctors have told women for a long time that there is a greater risk to having children when one is in their thirties.
Matt Freeman | Jul 19, 2012 | Reply
Very interesting!!
jennifer eiffel01 | Jul 19, 2012 | Reply
This was the reason I don’t have a brother because daddy didn’t want my mom to haVe another baby because my mom had me when she was 30 years old and in the early 1970s you didn’t have babies that old. My sister and cousin both had their babies in mid to late 30s and ther kids turned out great. They are all ‘normal’ and have no problems and are all adoreable!
drabiakhan | Jul 19, 2012 | Reply
ya. but 30 yrs is ok. 35+ matters more. Anyways i am happy to see the comments back
Aroosa Gloomy | Jul 19, 2012 | Reply
Thanks dear
stevetheblogger | Jul 19, 2012 | Reply
What another wonderful article you have written learn t things all the way through the read.
Best Wishes
stevetheblogger
smokychristine | Jul 20, 2012 | Reply
Downs Syndrome babies are a disaster for most, but those special chilodren give a lot to their families. They are extremely loving for the most part.
drabiakhan | Jul 20, 2012 | Reply
ya they are. And parents mostly try to develop specific skills in them to help them live a better life.
sabanawaz | Jul 20, 2012 | Reply
great share.Agree with smoky
drabiakhan | Jul 20, 2012 | Reply
thanks for appreciation. Read also about diseases associated with paternal old age in the below article:
http://healthmad.com/conditions-and-diseases/achondroplasia-related-to-advanced-paternal-age/
eaa1118 | Jul 20, 2012 | Reply
Achondroplasia for aging males and Down’s for aging females…
Fair enough, right?:-) None of the sexes left out…
Very interesting, by the way.
Thank you:-)
drabiakhan | Jul 22, 2012 | Reply
ya:) diseases tend not to spare any sex nor age. so spread the word to avoid abnormalities in future generations.
Tiki33 | Jul 22, 2012 | Reply
Thanks for sharing this informative article.
Karen | Jul 22, 2012 | Reply
My daughter ( who I had when I was 23), had a baby with Down’s when she was only 22.
I also had another typical child in my 39th year, so age isn’t always the determining factor when it comes to chromosome abnormalities.
gaby7 | Jul 23, 2012 | Reply
Absolutely informative Dr. Drabia! You are truly broadening our knowledge on health issues!
Sustainable Living | Jul 23, 2012 | Reply
Very interesting and well researched.
drabiakhan | Jul 23, 2012 | Reply
thanks for the compliment. read also
http://healthmad.com/conditions-and-diseases/achondroplasia-related-to-advanced-paternal-age/
ayesha1986 | Jul 24, 2012 | Reply
so informative!
JoniJones | Jul 27, 2012 | Reply
Thanks for the info
papaleng | Jul 27, 2012 | Reply
Shared this one to one of my friend.
Margaret Boseroy | Aug 10, 2012 | Reply
Very informative. Thanks for this post.
Shawn Lyrics | Aug 15, 2012 | Reply
wow very Interesting, I knew there were complications but didnt realized how severe it could be.
Jswana | Sep 6, 2012 | Reply
My son came out normal at my advanced age of birth but the possibility is of course greater as we age. I am with a former commenter Karen, age isn’t always the factor but definitely something to think about. Thanks for sharing.:)