Genes Affect Sleep Patterns.
Genes Affect Sleep Patterns
Many believe that the habit of waking in the morning or afternoon, due to the fast or slow a person goes to sleep. But according to studies, it is precisely due to the influence of the person’s genes.
Scientists say they have found more evidence that the habit of waking up in the morning and afternoon, it happened due to individual genes. Researchers say this discovery, has helped to understand better how the human body works and its effect on sleep disorders. As they say, to bed early wake up too early. In the world of sleep research problems can be called as a disease, symptoms are the same as those who have trouble sleeping at night.
The human body works with 24-hour cycle. This natural mechanism known as Circadian rhythms, which determines how long we sleep and when. The researchers, including a neurologist Louis Ptacek of the Howard Hughes Medical Institute, discovered a defect in a gene known as Per2 Circadian rhythm that regulates it. This week in the journal Nature, Dr. Ptacek and colleagues at the Howard Hughes Medical Institute University of California at San Francisco reported the discovery of mutations in other genes, known as CK1 delta.
“If you imagine it like a rotation of toothed wheels in a clock, if the movement is too fast there may be a problem in one wheel or the Per2 gene, a mutation may also occur in a different wheel, in this case, CK1 delta.” Clearly The researchers found a defective gene in a family of people who get up early. When the gene is inserted into the body of mice, the animals showed a similar behavior. When the same genes injected to the fruit fly, can disrupt their circadian rhythm. Dr. Ptacek said, using the same gene to study the behavior of different species, may be encouraging the discovery of the molecular mechanisms involved in sleep disorders. He estimates that three out of 10 people has some form of sleep disorder.
He said the research on genes that regulate the body clock can lead to the discovery of sleep disorders medicine at the men. With age, he said all people have a tendency to sleep early and wake up early. In some cases, it is a problem for seniors who woke up when the cold weather, dark and lonely. “So we think the findings are normal with age is another example where a drug that helps us adjust our body clocks will probably improve the quality of life for the better.” he said
The researchers said the six family members who learned it as waking up earlier also had asthma, depression and headaches. Scientists believe there may be a link between the disease with sleep disorders. Tom reflexology Feroah from the Medical College of Wisconsin in Milwaukee, has been researching the mice are almost identical to each other and causing gene infer differences in sleep patterns are different.
Professor Feroah said, it is not surprising that people who suffer from sleep disorders suffer from various diseases. He said, Circadian rhythms regulate a series of small jamjam contained in each cell, which ultimately regulate the immune system, temperature regulation, hormone and brain functions of the brain.
“So, there is a combination of all bodily functions, where we try to sleep out of the habit, as familiar with the TV or because there are lights of our lives as if they mess up the whole body function. It makes us feel more depressed and not able to also release stress, and not sleeping well, do not heal normally if they were sick and have a tendency to suffer from the disease, “said Feroah.
People who do not sleep well and not be able to sleep at the beginning of sleep, suffer more heart disease, high blood pressure and stroke, researchers said was due to interference with the immune system.
The researchers hope to find more sleep genes. Laboratory studies have so far shown little change in Delta CK1 gene that seems to calm the activity of proteins interfere with sleep. It may be good news for people who can not get a good night’s sleep.