The Worst Disease Outbreaks
Black plague and Spanish flu were both highly pathogenic influenzas that caused high mortality rates. They existed as killer plaques for a longer interval cycle. By the end of the 20th century, livestock and poultry-related pandemic flu caused many deaths in humans. About 15 years later in 2002-3, SARS hit hard in China, and within a short period of six years, H1N1 has now swept over the globe tremendously, causing deaths in Mexico, America, Europe and Asia. When next confronted with these highly contagious plagues, deadly diseases or flu-like symptoms, who will become an innocent victim?
Cholera


According to WHO, there have been seven pandemic outbreaks of cholera and in 1999 alone; over 9,000 deaths were recorded on the course of cholera. In human history, the British Army has a record of 100,000 cholera deaths among its troops.


Cholera (Asiatic or epidemic cholera) is transmitted via drinking water or eating foods contaminated by choleravibrios from other cholera patients. It’s an infectious disease caused by the bacterium Vibrio cholerae which produces cholera toxin (an enterotoxin which interferes with the mucosal epithelium lining of the small intestine) and may cause severe, exhaustive diarrhea.

Therefore, it’s possible to die within the onset of symptoms or within hours of contracting cholera, as a healthy person’s blood pressure may drop to hypotensive level. Without a prompt oral rehydration therapy being given, a person may experience an extremely low blood pressure, the first stool to shock in 4 to 12 hours, heart failure, followed by death from 18 hours to several days. It seems that proper sanitation, clean water and hygiene are important elements to keep not get cholera infection.
Enteroviruses

Enteroviruses are diverse group of small RNA viruses that can cause non-specific viral infection to mild respiratory diseases (such as common cold), aseptic meningitis, severe neonatal sepsis-like disease, acute hemorrhagic conjunctivitis, foot, mouth and hand disease, acute flaccid paralysis, and myocarditis (inflammation of the heart), particularly in infants.


Other types of the species are coxsackie A viruses (CA), coxsackie B viruses (CB), enterovirus 71 (or EV71 can cause rashes, diarrhea, food, hand and mouth disease and in severe case, EV71 may also cause severe neurological disease) and polioviruses. The viruses may be transmitted via direct contact with secretions from an infected individual or by contact with any contaminated objects or surfaces (such as telephone, mouse, drinking glass), and one may also get infected with the viruses by contamination of hands with feces from an infected toddler or children during diaper changes.

Kids or infants who get infected with enterovirus 71 (a fatal strain) may have a mild fever or spots around their mouths, and this virus is highly lethal as it may cause sudden death among children as reported in the late 1990s in Asia, where its outbreak had claimed the lives of about 40 kids (below six years old) in Southern China.
Dengue Fever


Dengue fever (also called breakbone fever or dandy fever) is an acute disease transmitted by infected mosquito (Aedes aegypti or the Aedes albopictus mosquito). Each year, according to WHO, about 50 million cases of dengue infection are reported worldwide and about two fifth of the world’s population is at risk for dengue fever. Furthermore, this disease is now regarded as an epidemic in over 100 countries. In 2008, about 100,000 people in Rio deJaneiro had been identified to be infected with dengue.

Its sudden onset is normally accompanied by a benign course of severe joint, muscle pain, headache, fever, swollen glands (lymphadenopathy), rash and exhaustion. That explains why victims of dengue always experience distortion due to acute muscle pain and intense joint. In severe case, one may have bleeding in the gums or nose, black feces, petechiae (purple or small red blisters below the skin), which are a severe form of a deadly hemorrhagic fever, and it can be fatal or even life-threatening.
Ebola


Ebola is a terrifyingly viral disease that can cause substantially high fatality rate in human since Ebola virus can invade human cells causing severe internal bleeding. The worst outbreak of this disease occurred in 2007, resulting in 187 deaths. The most deadly strain of Ebola, the Zaire strain has been identified in Sudan, Uganda and Congo, while the non-fatal strain of Ebola, the Ebola-Reston strain has been identified in Philippines, Italy and the United States. Human is infected with Ebola virus via direct contact with bodily fluids, mucous membrane and skin of infected persons, and even airborne particles. Muscle pain, vomiting, fever, diarrhea are some of its common symptoms, but in a severe case, one may experience skin rash and internal bleeding.
H1N1



Image source Image source Image source
Swine flu (also called swine influenza, influenza A (H1N1), flu) is a respiratory disease among the pig populations caused by A influenza virus, in which its outbreak normally occurs in the colder weather months (late fall and winter). In 1930 in the United States, an influenza type A H1N1 virus has been known to circulate among pigs. The current swine flu H3N2 viruses are closely associated with human H3N2 viruses (quoted from my previous article entitled three scary flu pandemics that raged fiercely over the world). H1NI virus is highly contagious and it can be transmitted from pigs to humans, from humans and pigs, but the most worried one is that it can be transmitted from humans to other humans. The latest cases of swine flu show us that the viruses are transmitted from person to person via coughing and sneezing (quoted from my previous article entitled swine flu sweeps across the globe: will it be the seventh killer plaque in history?).
Additional info:
Sore throat, fever, cough, runny nose, headache and tiredness are common symptoms of H1N1. In adults, severe and persisting vomiting, breathlessness, chest pain, purple or blue discoloration of lips, dizziness while standing, absence of urination, being less responsive than normal drowsy, seizure, and signs of dehydration are emergency signs of H1N1, while in children, poor feeding and lack of tears while crying. When you come across someone with the above stated signs and the symptoms worsen, please consult your nearby doctor immediately.
High risk groups of H1N1 or influenza-related complications include children (below 5 years old), those on dialysis, immunosuppressant, long-term aspirin therapy; those who are undergoing cancer treatment, pregnant mom, persons who aged 65 years and above and those who have underlying medical conditions (such as chronic lung disease, diabetes, kidney disease, heart disease, asthma, breathing problem).
To avoid/prevent getting H1N1, please take precautionary steps as follow:
- If you’ve been given a medical leave, please stay away from work and school until the end of leave period.
- Maintain indoor ventilation and sanitation.
- Wipe/wash off surfaces which are tainted with phlegm, nose discharge, sputum or any impurities with diluted household bleach (one part of bleach ratio to 50 parts of water) immediately. Use 70% alcohol to wipe off the tainted metallic surfaces.
- Keep distance of 2m from each other or when you contact with anyone in the public places. Protect yourself by wearing surgical mask, and by using hand sanitizer to kill the germs.
- Keep yourself at home if you don’t have the obligation to be out. Replenish yourself with adequate amount of water to avoid dehydration.
- Avoid having meals with H1N1 infected person.
More effective precautionary steps against H1N1, kindly visit swine flu sweeps across the globe: will it be the seventh killer plaque in history?
AIDS/HIV

AIDS is by far the scariest disease since it has killed 25 million people since 1981. Worldwide, approximately 33 million people are diagnosed to be infected by AIDS virus, and 22 million of them are diagnosed among people in sub-Saharan Africa. According to the National Center for Health Statistics, about 15,000 U.S. residents died from the AIDS/HIV in 1999.


HIV, or scientifically known as Human Immunodeficiency Virus, is a type of virus that attacks the cells of living organisms by making new copies from the original “codes” (means make up the human body and replicate within those infected cells), weakening immune system (a natural defence against disease), while attacking a particular immune system cell called CD4 lymphocyte. When the immune system is weakened, it leads to chronic and progressive illness. The HIV then advances to a stage of illness called AIDS, or Acquired Immunodeficiency Syndrome, causing the infected individuals vulnerable towards other infections and illnesses. As it is regarded as an opportunistic disease, it may also lead to death (quoted from my previous article entitled Understanding Aids/HIV: unveiling the hidden facts. Also read: Little Known Facts About AIDS -more pictures here).
Spinal Meningitis


Spinal Meningitis is a disease that can infect the fluid around the brain and spinal cord, and severe case of this infection can cause an unexpected brain damage or even death if prompt treatment is not given. Its outbreak is more frequent in the northern region of sub-Saharan Africa, which was reported to kill over 2,000 people in Chad, Niger and Nigeria since 2009. In 1996 alone, more than 56,000 cases were reported, with 25,000 people died on the course of Spinal Meningitis infection.
SARS


This severe acute respiratory disease can mutate very rapidly but before the outbreak of SARS in 2003, no one paid full attention to this virus which can cause common cold/flu-like symptoms. Nevertheless, condition changed when SARS had been reported to kill doctors and nurses, while showing its pandemic levels in China and Hong Kong, which held the world’s attention.

In the same year, SARS has become a global concern as it is a new and deadly disease that appeared suddenly in the human history. The air travel and the globalization of the live poultry market reflect that this virus has a good medium to sweep across the globe only within a few months (quoted from my previous article entitled scariest, deadliest disease). Read more details on SARS by visiting my previous article entitled The deadliest and most horrible diseases that shock the world.
Black Death


As like the scary pandemic of Spanish Flu of 1918, Black Death (1347-1351) is the scariest infectious disease that caused a mortality rate of 100%.

It’s by far a pneumonic form of the plague that had killed about 34 million people in Europe, and the same figure had also reported in both India and China. In about 200 years, this epidemic outbreak of bubonic plaque had taken away 100 million lives worldwide. It’s said that this plaque was caused by the bacterium Y.pestis, however, some scientists said it may have caused by anthrax or an Ebola like virus.
MRSA

MRSA is a highly contagious superbug that has now caused a major health concern among the public. Once infected, its pain is beyond the description of words. A study of Centers for Disease Control and Prevention stated that about 94,000 Americans were seriously ill and 19,000 were reported killed after getting infected with MRSA.

While bacteria that healthy individuals can carry on their skin or in their noses is commonly referred to as “staph” and generally minor, we should be cautious. They may appear as pimples or boils. Staph infections can spread into the blood, bones and lungs and sometimes are resistant to treatment (quoted from article written by Judy Sheldon, More Deadly than Aids, with permission).

For the sake of your health, you should stop the spread of MRSA by taking necessary precautionary steps as follow:
- Wash your hands frequently before touching others or any materials.
- Prompt your doctor or nurse to wash their hands before touching you.
- Avoid sharing your personal items (such as razors, towels, swimming suits, clothing, combs) with others.
- Apply healthy living habits and strict personal hygiene
- Make sure you keep your cuts or abrasions disinfected, bandaged, washed or closed properly to avoid the spread of MRSA.
- If there is a serious outbreak of MRSA in your area, make sure you wash your hand with water thoroughly every 60 minutes.
Now, you can gain more health knowledge by visiting my health blog entitled HealthAssist. More upcoming updates and latest health information are right on the way!
Liked it


raman13 | Aug 14, 2009 | Reply
Good Stuff
Thanks
Now your turn
Best Regards
lindalulu | Aug 14, 2009 | Reply
Wow..Chan what an informative article! Too bad so many terrible diseases have to exist. The outbreak of any thing is horrible and the victims of such things should make the world step up and take more notice. Hopefully with articles this this one they will….
CA Johnson | Aug 14, 2009 | Reply
What an interesting article Chan! I feel so sorry for all of those poor people who have to suffer with those terrible diseases.
Hugo La Rosa | Aug 14, 2009 | Reply
Chan: Thank you for the information. I have heard about Cholera, but really didn’t know much about the ravaging conditions of the disease. The pictures are very illustrative. Now I know what Gabriel Garcia Marquez is talking about in his book “Love in the Time of Cholera”. Best Regards, Hugo.
Uma Shankari | Aug 14, 2009 | Reply
All the troubles you take for writing an article are worth it, Chan. That’s why you produce consistently informative and riveting articles. Kudos.
thestickman | Aug 14, 2009 | Reply
Excellent, well-documented article Chan. Thanks!
bjr | Aug 14, 2009 | Reply
great article.people need to see this kind of information.
Jenny Heart | Aug 14, 2009 | Reply
I know someone who has Mrsa. It’s a never ending battle. Keeping the immune system built up is of vital importance. great informative article.
PR Mace | Aug 14, 2009 | Reply
Chan, you write the most well done, well researched articles. Do you have a medical background? Another outstanding piece. Well, well done.
Christine Ramsay | Aug 14, 2009 | Reply
A very impressive, informative and beautifully presented article, Chan. Brilliant work.
Christine
Joe Dorish | Aug 14, 2009 | Reply
Well presented article Chan, liked it a lot!
Juancav | Aug 14, 2009 | Reply
Detailed, pests and diseases that have affected the world.
Ruby Hawk | Aug 14, 2009 | Reply
So many terrible diseases, We are lucky that most of us escape them.
valli | Aug 14, 2009 | Reply
Scary and terrible diseases. Thanks for the well researched info, Chan.
Judy Sheldon | Aug 14, 2009 | Reply
Chan, your articles are always so well researched. Thanks so much for providing us with necessary information to safeguard our health and that of our loved ones.
Goodselfme | Aug 15, 2009 | Reply
Very educational, well composed along with the pics to make this a completely thought out informative piece.TX
RJ Chamberlain | Aug 15, 2009 | Reply
Chan,
Very informative mate. Thank you.
RJ
Pacific Mists | Aug 15, 2009 | Reply
The disease information shown here is staggering. Wow, so many people are suffering so terribly throughout history, and presently.
Good work putting together such extensively researched information, Chan.
nobert soloria bermosa | Aug 15, 2009 | Reply
a very well research post,helpful and informative as well
BC Doan | Aug 15, 2009 | Reply
Very informative article Chan! The pictures show how terrible and serious the diseases are..
chitragopi | Aug 15, 2009 | Reply
Highly informative. Reads like a reasearch article by an experienced specialist doctor. Thank u for the information and precautions.
Mr Ghaz | Aug 15, 2009 | Reply
Excellent!..A very informative and educational article. well done!..very well written with superb pics. Thanx for sharing this great work.
Parul | Aug 15, 2009 | Reply
A great article. You have done a lot of research. The article is very informative.
Lauren Axelrod | Aug 16, 2009 | Reply
Well done Chan. At my college, children are completely banned from the computer labs because they spread so many germs. Especially now, with several cases of swine flu nearby.
DA Cournean | Aug 16, 2009 | Reply
Great article..well presented.
deep blue | Aug 16, 2009 | Reply
Another well researched article my friend. Well done and best regards.
Will
giftarist | Aug 16, 2009 | Reply
Very informative, interesting and well-written article.
Two-thumbs up for you,
Research is worth it
AngelaDavid | Aug 17, 2009 | Reply
Well written article here. Informative.
Anne McNew | Aug 17, 2009 | Reply
you have presented those very important views about diseases. thanks for sharing this.
CutestPrincess | Aug 18, 2009 | Reply
that must be a good info for us to be aware of something very important. thanks for sharing
Mys Lyke Meeh | Aug 18, 2009 | Reply
Holy Moly, those were scary and terrible diseases. Yet, good enough that you put up those kind of pictures, for people to know and be aware of how people should be alarmed and can do something about it before it affects on them.
A very good job. 10/10 rate.
Kate Smedley | Aug 19, 2009 | Reply
Well researched and informative article, these diseases are so frightening. Excellent work Chan.
ESTRELLA 2008 | Aug 20, 2009 | Reply
EXCELENTE ARTICULO AMIGO COMO TODO LO QUE TU ESCRIBES YA EXTRAÑABA LEER TUS ARTICULOS.
Andromeda | Aug 28, 2009 | Reply
Chan, you’re the “King of EWWW!” Thank you for reporting on these epidemics. I am so glad you added information about how to take care of cuts, scrapes and rashes. As smart as people are, or claim to be, they tend to be selfish and not think about covering their mouths when they cough/sneeze, washing their hands often or covering abnormal skin areas while they are sick. Folks think , “I’m sick so I don’t really care if someone gets sick from me”. Additionally, I would like to add that the same folks that come into the grocery store and wipe the cart handle with the provided sanitizer wipes because they think “Eww germs!” are the same people who dip their dirty, unwashed hands in the bulk bins and sample trays without using a tissue…(staph lives on skin) the same people who go to work when they are contagious to be “a team player”. Employers WANT you to stay home if you’re sick. Why would they want an office-full of sickly people? Being a team player is staying home when you are sick. Thanks for allowing my long comment. Great article Chan!
Joshua Miguel | Aug 31, 2009 | Reply
wow! this is so informative and so much work was put into this post. nice one and keep it up.
Mr Ghaz | Sep 4, 2009 | Reply
A wonderful tips and highly informative article..well researched too..I loved it.Thanks for sharing this fab. piece.