Inositol: Isomer of Glucose

Inositol is an isomer of glucose that occurs naturally. There are nine possible stereoisomers, the most important form is myo-Inositol. Myo-Inositol was initially considered a member of the vitamin B complex (B8). Because the human body has some capacity to synthesize Inositol is no longer classified as a vitamin.
Features Inositol.

Inositol is an isomer of glucose that occurs naturally.  There are nine possible stereoisomers, the most important form is myo-Inositol.  Myo-Inositol was initially considered a member of the vitamin B complex (B8).  Because the human body has some capacity to synthesize Inositol is no longer classified as a vitamin.
Features Inositol

Inositol is an important intermediate in the intracellular phosphatidyl Inositol second messenger activated by numerous serotonergic, cholinergic and noradrenergic.  Other biological processes include:

* Insulin signal transduction
* Mounting cytoskeletal
* Structure nervous
* Regulation of intracellular calcium
* Maintenance of the cell membrane potential
* Modulation of serotonin
* The distribution of fat and reduce cholesterol
* Gene expression
* Strengthens the hair cells

Phytate and Inositol

Phytic acid (known as Inositol hexakisphosphate (IP6), or phytate when in salt form) is a strong chelator and is the main storage form of phosphorus and other minerals and trace elements in plant material.  Phytic acid found in the shells of nuts, seeds and grains.  Phytic acid may have a negative effect on nutrition that may affect the absorption of calcium, zinc, iron and magnesium and other minerals and niacin, a vitamin.  Inositol is released from phytic acid in the digestive process.

probiotic lactobacilli and other species in the gut microflora, and are an important source of phytase enzyme that catalyzes the release of phosphate, mineerals and trace elements, making them more soluble and to improve their intestinal absorption.  This underlines the importance of maintaining a healthy intestinal flora, especially with a diet emphasizing grains.

Just cooking reduces phytic acid to some extent.  The most effective methods is lactic acid fermentation, and germination.

Potentially adverse nutritional effects of phytic acid in foods is also strongly influenced by the availability of minerals in the diet and soil as food is grown.

Given the therapeutic benefits of phytic acid and the potentially negative effect of phytic acid on the absorption of nutrients, it is advisable to take a point product IP6 combined with food.  It is also advisable to use a mineral and trace mineral supplement.  Taking supplements that Inositol does not seem to affect the absorption of minerals.
Inositol in depression, panic disorder, agoraphobia, and bulimia

Patients suffering from clinical depression have been found at reduced levels of Inositol in the cerebrospinal fluid.

High doses of Inositol (12 grams per day) has shown promising results in patients suffering from bulimia, panic disorder, obsessive-compulsive disorder, agoraphobia and unipolar depression and bipolar.

Scientists believe that Inositol produce positive clinical outcomes in patients suffering from depression because of phosphatidyl Inositol acts as an intracellular second messenger serotonin receptor signaling mechanisms.  It is therefore possible that Inositol can be used as a synergist of 5HTP or SSRIs.

The results of studies using Inositol with bulimia, panic disorder, obsessive-compulsive disorder, agoraphobia and depression are very positive and side effects minimal or nonexistent.  But these disorders are complex devices and the use of Inositol as a treatment modality should be considered as part of a doctors advice.
Inositol and cancer

Inositol hexaphosphate, or IP6 phytic acid, is a form of Inositol.  IP6 forces malignant cells to revert to a non-cancerous condition, a phenomenon observed in human cells and other cell lines of colon cancer.

IP6 combined with Inositol use is considered more effective than using IP6 alone.

IP6 is a powerful antioxidant, and an agent that modulates the cancer, but when taken with food, IP6 binds with proteins, forming insoluble complexes so easily metabolized and absorbed compared to when alone.  For therapeutic effect, the use of supplements more effective than whole foods.

IP6 reduces the rate of cell proliferation, both in vivo and in vitro and reduces the synthesis of DNA.  IP6 include the promotion of natural defense mechanisms by increasing natural killer cells (NK) cells, blocking PI-3-kinase, an enzyme that is required for tumor promotion, change of mobile communication is required for growth tumors by stimulating the tumor suppressor genes, and inhibition  of metastasis and angiogenesis blocks (the formation of new blood vessels that liver tumors).

Another possibility is the role of IP6 as a chelating agent.  Iron and other minerals are important in gene regulation.  Studies have shown a possible link between excess iron and increased risk of cancer in animals and humans, especially colon cancer.  IP6 has been shown to affect iron absorption and increased iron-dependent reversal of the initiation of colorectal tumors.  IP6 also removes iron caused by free radicals and inhibit lipid peroxidation due to iron.

if you are using IP6 as anticancer agent was tested in vitro (laboratory) and in animals.  The use in humans has not been thoroughly tested in clinical trials.  Although the results are promising and the side effects are minimal or non-existent, can be used for cancer treatment at medical care.
Osteoporosis and Inositol mineral nutrition

There is a difference between the chemicals and minerals from the phytic acid binding Inositol in plants.  The effect of phytic acid and phytate on mineral nutrition is influenced by a number of variables.  These variables are the abundance of minerals in the diet, the condition of probiotic bacteria in the digestive tract of humans and the use of food processing, such as lactic acid fermentation and germination.  Although phytic acid is a strong chelator of iron, there was no evidence that phytic acid associated with iron deficiency.  Although phytic acid can combine with calcium and other minerals, there was no evidence linking the consumption of phytic acid with osteoporosis.  In fact, some evidence has been reported that Inositol and phytate complex can reduce the incidence of osteoporosis.
Phytic acid (IP6) as a chelating agent

Phytic acid (IP6) is a chelating agent.  Has been used clinically as a chelating agent to remove uranium from the body.

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