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Women’s Health Issues: Ovary Syndrome Polikista

Polikista ovary syndrome (Stein-Leventhal syndrome) is a disease in which the ovaries (ovary) enlarged and contain many fluid-filled sac (cyst) levels of male hormones (androgens) can be so high that sometimes causes masculinization.

Women’s Health Issues: Ovary Syndrome Polikista

Polikista ovary syndrome (Stein-Leventhal syndrome) is a disease in which the ovaries (ovary) enlarged and contain many fluid-filled sac (cyst) levels of male hormones (androgens) can be so high that sometimes causes masculinization.

This syndrome is usually the pituitary gland releases a large amount of LH (luteinizing hormone). Excess LH leads to increased formation of androgens and androgen levels are high this is sometimes cause acne and coarse hair.

If left untreated, some androgens can be converted into estrogen and high estrogen levels may increase the risk of cancer of the uterine lining (endometrial cancer).

CAUSE
The cause is not fully understood, but some of the theory is a disturbance in the formation of estrogen and the feedback mechanisms of both ovaries, the hypothalamus. Normal ovarian function is dependent on a number of hormones and the failure to establish one of these hormones can affect ovarian function. Ovaries will not function normally if the woman’s body does not produce pituitary hormones in the right quantities.

Abnormal ovarian function sometimes causes the accumulation of follicular imperfectly formed in the ovaries. Follicular maturation and failed failed to release the egg, thus forming cysts in the ovaries and cause infertility in women.

Ovaium polikista has a size of 2-5 times larger than normal ovaries and has a white outer layer, thick and very strong. This syndrome usually appear soon after puberty.

Patients often have a mother or sister who also suffers polikista ovary syndrome.

SYMPTOMS
Symptoms usually appear at puberty, which are:

    Obesity
    Hirsutism (excess hair growth that follows the male pattern, such as hair grows on the chest and face)
    Oligomenorrhea (abnormal menses, irregular and less)
    Amenorrhea
    Sterility
    Mengecilecreased breast breast size
    Pimple
    Virilization (masculinization, signs of virility).

Diagnosis
Diagnosis based on symptoms and physical examination (pelvic exam).

Regular checks carried out:

    LH and FSH levels (LH and FSH ratio is usually increased)
    Vaginal ultrasound
    Laparoscopy
    Ovarian biopsy
    Levels of androgen, estrogen.

TREATMENT
Treatment depends on the type and severity of symptoms, patient age and pregnancy plans.

In the absence of hirsutism, can be given progentin synthetic or birth control pills. However, both drugs were not administered if the patient wants to get pregnant, have entered menopause or have a high risk of heart disease and blood vessels. Synthetic progestin was also given to reduce the risk of endometrial cancer due to high levels of estrogen.

To reduce excessive hair growth can be done by electrolysis shaving, plucking, use wax or liquid or cream hair thresher (depilatori).

Excessive hair growth can also be treated with spironolactone (a drug that inhibits the formation and action of male hormones).
Side effects of spironolactone was increased formation of urine, low blood pressure, chest pain and irregular vaginal bleeding. Spironolactone can also cause impaired fetal growth, because it is patients who received spironolactone should use contraception.

If people still want to get pregnant, can be given clomifene (a drug that stimulates the release of eggs from ovaries). If clomifene is effective, can be given a number of hormones (eg FSH or GnRH). If the provision of drugs are not effective, patients could undergo surgery to remove most of the ovary (wedge resection) or cautery cysts (cysts with an electric current to destroy). Surgery can stimulate the release of eggs, but usually the last option because it can cause scarring and decrease the ability of patients to become pregnant.

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  1. nice share….

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