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I Owe Statins My Life

These tablets are getting knocked in the media why?

I take statins every day so I thought I had better check on them because of scaremongering in the press.

Statins are a group of drugs that lower the risk of cardiovascular events such as heart attacks and ischaemic strokes – strokes due to clots in the arteries to the brain – and the need for interventions such as a heart bypass. The short name is “statin” because all the drug names end in it. Simvastatin and atorvastatin are two commonly available ones.

They inhibit a liver enzyme which is involved in making cholesterol; blocking it reduces the amount of cholesterol made in the liver. In response to that, liver cells put more receptors for a form of cholesterol known as LDL – sometimes called bad cholesterol – on their surface. Those receptors pull more LDL out of the blood, so lowering levels. That LDL cholesterol is metabolized by the liver and excreted.

Typically total cholesterol levels in blood might be between 4 or 5 millimoles per litre, most of which is LDL. Statins can reduce the LDL component by about 2 units, which can lower your risk of a major vascular event by about 40 per cent.

Simvastatin and atorvastatin are available in generic form, so their cost per patient in the UK is around £2 a month. They have become very cost-effective for the National Health Service.

There have been a lot of randomised, placebo-controlled trials done in a wide range of different types of patients, starting off in high-risk patients, typically people who already had coronary disease. As the evidence emerged of both safety and efficacy, more recent trials looked at patients with lower risk factors, such as diabetes alone, or high blood pressure. Again these show benefit. Finally, trials have also been done showing benefits even among people who didn’t have any of the classical risk factors for cardiovascular problems

Statins are very effective at preventing heart attacks and strokes and reducing the risk of vascular death, and have been shown, in very carefully controlled studies, to be safe.

Since having my strokes I have been taking Statins and so far they have worked well. That’s eleven years of a stroke free life and I can write articles like this.

I have other health problems but I can think again and come to correct conclusions that’s more than most people can do.

This is more than most politicians can do, could it be they are thinking of getting rid of statins?

We would be much better off getting rid of this government.

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